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Trisomy 18 is a disorder in which babies are born with 3 copies of chromosome 18 instead of 2. For an unknown reason, this accident occurs at the time of conception and all cells in the body will have this structure. In 90-95% of the children with Trisomy 18 this is the case. In 5-10% of infants with Trisomy 18, only a portion of their cells may contain the extra chromosome 18 (called the mosaic type of Trisomy 18). Infants with Trisomy 18 will usually be small at birth and have a recognizable appearance caused by the extra chromosome. Some of these features include: prominent back of the head; small eyes, mouth, and jaw; unusual looking ears; clenched fist with overlapping fingers and thumbs; small fingernails; clubbed or rocker bottom soles of the feet; a short breastbone (sternum); and extra skin folds at the back of the neck.

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Trisomy 18 occurs at a rate of 1 in 2000-6000 live births. It is somewhat more common as the mother ages but can occur randomly to parents of any age. Most babies affected are girls. There is no known cause of Trisomy 18. Studies have shown that only 50% of babies who are carried to term will be born alive. The median of survival among live births has varied between 2.5 and 14.5 days. About 90% - 95% of babies do not survive beyond the first year and many live only a few days.

At the same time, CBS is going to think about the 2021-2022 season that begins in September 2021. If we want NCIS Season 19 and we want it to premiere in September, filming needs to start in July 2021. That is only possible if filming for the current season stops around April or May.

Approximately 5 percent of people with trisomy 18 have an extra copy of chromosome 18 in only some of the body's cells. In these people, the condition is called mosaic trisomy 18. The severity of mosaic trisomy 18 depends on the type and number of cells that have the extra chromosome. The development of individuals with this form of trisomy 18 may range from normal to severely affected.

Very rarely, part of the long (q) arm of chromosome 18 becomes attached (translocated) to another chromosome during the formation of reproductive cells (eggs and sperm) or very early in embryonic development. Affected individuals have two copies of chromosome 18, plus the extra material from chromosome 18 attached to another chromosome. People with this genetic change are said to have partial trisomy 18. If only part of the q arm is present in three copies, the physical signs of partial trisomy 18 may be less severe than those typically seen in trisomy 18. If the entire q arm is present in three copies, individuals may be as severely affected as if they had three full copies of chromosome 18.

There are really two problems here, although only one appears on the surface. Should the proper translation be "only begotten Son" or should it be as the New American Standard Version renders it, "only begotten God"? This particular problem is not translational but textual because there is a difference in the Greek texts underlining these two translations. However, there is another problem that has to do with the Greek word monogenes. Both the King James and the New American Standard correctly translate it as only begotten. There is a growing movement to understand this word as unique, one of a kind, or simply only. We will deal with this difference first.

Many of the current handbooks on Greek syntax state that monogenes should not be translated as only begotten. [1] Instead, they take the word to mean only or unique. If this were true, the translation of the KJV would not be alone in its "error" for this is the translation of the New American Standard Version, the New King James Version, and several other translations of the twentieth century.

The problem here is a misunderstanding of the Greek language (both Koine and Modern). The word monogenes does means one or unique in the sense that an only child is the only one of his parents. It does not mean unique, as in special, such as in the phrase, "his work is very unique." Here the Greek would be monadikos, not monogenes. As we examine the New Testament we find the word monogenes used eight times (not counting its usage here in John 1:18). In every case it is used to describe a relationship between a parent and child (Luke 7:12; 8:42; 9:38; John 1:14; 3:16, 18; Hebrews 11:17; 1 John 4:9). Since this is how the Holy Spirit uses the word in the New Testament, we must accept this definition when reading John 1:18. [2]

The evidence establishes that Jesus Christ, although God (John 1:1), is also the only begotten Son of God. None other can claim hold to this title. Those who accept Christ as their personal Savior are spiritually born of God and are called His sons (John 1:12). But no human can lay claim to the title of only begotten Son. This phrase has not only to do with Christ's virgin birth, but also His eternal place within the Trinity.

Having established this point, we are now faced with the question of the word following monogenes. Should it be heios (Son) or theos (God)? The oldest known Greek manuscripts, P66 and P75, read only begotten God. However, these manuscripts all come from the Alexandrian line and smack of ancient Gnosticism. The Gnostics taught that Christ was a begotten god, created by God the Father, whom they called the Unbegotten God.

When those who had been tainted with Gnosticism cite John 1:18, they cite it as only begotten God. Such is true of Tatian (second century), Valentinus (second century), Clement of Alexandria (215 AD), and Arius (336 AD). On the other hand, we find many of the orthodox fathers who opposed Gnosticism quoting John 1:18 as only begotten Son (Irenaeus, Tertullian, Basil, Gregory Nazianzus, and Chrysostom). [3]

Even some that served on the textual committee for the UBS-4 recognized that the proper reading of John 1:18 is only begotten Son. Dr. Allen Wilkgren, who served on the committee, writes, "It is doubtful that the author (i.e., John) would have written monogenes theos, which may be a primitive, transcriptional error in the Alexandrian tradition." [4] Additionally, Professor Bart Ehrman of the University of North Carolina at Chapel Hill has noted that he believes the original reading is monogenes heios and not monogenes theos. [5] Although Professor Ehrman did not serve on the UBS-4 committee, he is a recognized scholar in the field of Biblical textual criticism. [6] Thus, not all scholars agree as to the original reading in this regard.

This hand colored wooden engraving by illustrator Henry Ogden depicts the wedding of Ellen Wrenshall Grant to Algernon Sartoris on May 21, 1874 in the East Room of the White House. Ellen, more often referred to as Nellie, was President Ulysses S. Grant's only daughter. She was 18 at the time of her wedding to Sartoris, a well-to-do English singer. This engraving was published in "Frank Leslie's Illustrated Newspaper" on June 6, 1874.

By the numbers: All 50 states either commemorate or observe Juneteenth but only 18 observe it as a permanent paid state holiday, those being Colorado, Connecticut, Delaware, Georgia, Illinois, Louisiana, Maine, Massachusetts, Maryland, Nebraska, New Jersey, New York, Ohio, Oregon, South Dakota, Texas, Virginia and Washington.

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As stated in the CSDE Transition Bill of Rights for Parents of Students Receiving Special Education Services, Students with an individualized education program (IEP) have the right to:10. Request consideration for receiving transition-only services between the ages of 18 and 21 if all transition goals and objectives have not been met during their previous years in high school.

g. Transition-only services are typically discussed during the senior year of high school. h. Transition-only services are not needed for graduation but may include academic, vocational, and independent living activities that will help students meet their post-school goals.i. Transition-only services should be based in the local community to the greatest extent possible in order to prepare students for life after high school.

Stateful recently shared a Node.js announcement about the new test runner module coming to Node.js 18.0.0, which is scheduled for release on April 19, 2022. While the test runner module is a notable change to Node.js, it brings a potentially more significant change along with it: prefix-only core modules. This post explains what prefix-only core modules are and what you need to know about them.

'node:test' is the first core module that can only be imported using the 'node:' prefix. In order to use Node's new test runner, you must import 'node:test'. If the 'node:' prefix is not included, Node.js will attempt to load a module named test from userland instead.

As previously mentioned, the explicit distinction between Node core modules and userland modules is the biggest benefit of prefix-only modules. For the Node.js core project, this change also makes it significantly easier to introduce new modules. Because core modules take precedence over userland modules during module loading, introducing a new core module has historically been treated as a breaking change and sometimes involved reaching out to npm module authors to negotiate the use of a module name. Prefix-only core modules provide a clear delineation between core and userland, reducing much of the friction involved in adding a new core module. 041b061a72

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